The rate of surgical procedures for treating low back and leg pain is increasing in Europe, North America, and Asia. These patients may require post-surgical rehabilitation; however, little is known about the effectiveness of these rehabilitative interventions. With joint funding by Eurospine, we have been working on a systematic review and meta-analysis to understand the effectiveness and safety of post-surgical rehabilitation interventions for adults with low back and leg pain treated surgically. We have also systematically reviewed qualitative studies to understand the experiences of patients, healthcare providers, caregivers or others involved with the rehabilitation. This review will guide researchers, clinicians, patients, and other decision-makers to improve outcomes in this population. We presented some results during a CCA webinar on March 4, 2021.